Assessing fracture risk in people with MS: a service development study comparing three fracture risk scoring systems

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Assessing fracture risk in people with MS: a service development study comparing three fracture risk scoring systems

OBJECTIVES Suboptimal bone health is increasingly recognised as an important cause of morbidity. Multiple sclerosis (MS) has been consistently associated with an increased risk of osteoporosis and fracture. Various fracture risk screening tools have been developed, two of which are in routine use and a further one is MS-specific. We set out to compare the results obtained by these in the MS cli...

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Osteoporosis and fracture risk in older people.

Until the 1940s, when Albright associated osteoporosis with a defect of bone anabolism, it was not considered a disease entity but an inevitable consequence of the ageing process for which there was little remedy.1 Bisphosphonates, fi rst synthesised in the 1800s but in clinical use only since the 1960s, demonstrated that this process of age-related decline in bone was, in fact, modifi able.2 M...

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Cardiovascular Risk Factor Analysis in Patients with a Recent Clinical Fracture at the Fracture Liaison Service

Patients with a low bone mineral density have an increased risk of cardiovascular diseases (CVD) and venous thromboembolic events (VTE). The aim of our retrospective chart review was to investigate the prevalence of CVD, VTE, hypertension (HT), and diabetes mellitus type 2 (DM2) in patients with a recent clinical fracture visiting the Fracture Liaison Service (FLS). Out of 3057 patients aged 50...

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Fracture risk perception study: patient self-perceptions of bone health often disagree with calculated fracture risk.

BACKGROUND We sought to evaluate the concordance between self-assessed perceptions of fracture risk and actual risk calculated by World Health Organization's 10-year Fracture Risk Assessment Tool (FRAX). METHODS We collected demographic data, lifestyle information, osteoporosis knowledge, bone density test results, and treatment history from patients aged 50 to 75 years. Subjects rated their ...

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Evaluating osteoporotic fracture risk with the Fracture Risk Assessment Tool in Chinese patients with rheumatoid arthritis

This study aims to evaluate the discriminative and predictive capacity of the Fracture Risk Assessment Tool (FRAX) to determine the 10-year risk of osteoporotic fracture in Chinese rheumatoid arthritis (RA) patients.This study included 168 RA patients and 168 healthy individuals as controls. The Chinese mainland FRAX model was applied to calculate the 10-year risk of osteoporotic fractures, def...

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ژورنال

عنوان ژورنال: BMJ Open

سال: 2013

ISSN: 2044-6055,2044-6055

DOI: 10.1136/bmjopen-2012-002508